Human T-cell leukemia virus-associated membrane antigens: identity of the major antigens recognized after virus infection.

Human T-cell leukemia virus-associated membrane antigens: identity of the major antigens recognized after virus infection.

Specific antibodies to cell membrane antigens found on human T-cell leukemia virus (HTLV)-infected cells have been detected in Japanese patients with adult T-cell leukemia/lymphoma and in asymptomatic carriers, using a live cell-membrane immunofluorescence assay. Reactivity of the positive antisera was analyzed using radioimmunoprecipitation and NaDodSO4/PAGE with the HTLV-infected tumor cell l...

The Enigma of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Infection in Iran

Human T-cell lymphotropic virus type-I (HTLV-I) was the first human retrovirus associated with malignancy.  The prevalence of HTLV-I infection varies significantly in different regions of the world.  In this study, the prevalence of HTLV-I infection among ethnic Jews living in Shiraz, South of Iran, was investigated. 286 blood samples were obtained.  HTLV-1 antibody assay on serum samples was d...

Antibodies to human T-cell leukemia virus-membrane antigens in macaques with malignant lymphoma.

Gallo and co-workers first described human T-cell leukemia virus (HTL V), a type C retrovirus isolated from an aggressive case of cutaneous T-cell lymphoma [27, 28]. Cases of adult T-cell leukemia/lymphoma (A1LL) , a unique mature T-cell malignancy, have also yielded numerous other isolates of H1LV [23, 7, 17, 35, 10, 29]. ATLL is seen at increased levels in southwestern Japan and the Caribbean...

Study of the Association Between Human T-cell Lymphotropic Virus Type I Infection and Lichen Planus

Leukemia-associated Transplantation Antigens Related to Murine Leukemia Virus

Two BALB radiation leukemias are strongly rejected by hybrids of BALB with certain other mouse strains, although BALB mice themselves exhibit no detectable resistance whatever. Hybrids immunized with progressively increased inocula are resistant to 200 x 10(6) or more leukemia cells; their serum is cytotoxic for the leukemia cells in vitro and protects BALB mice against challenge with these BAL...